Mental Health

Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44)

The NIH and other research sponsors invest a significant amount of funds in the development of new technologies to study the brain and behavior, from basic and clinical perspectives, through a variety of mechanisms, including, from NIH, the R01, R21, R33, P01, P41, and P50 grants. This investment has produced a large number of technologies that include hardware (e.g., instruments, devices, etc.), software (e.g., computational models, informatics tools, data analytic methods, etc.) and wetware (e.g., cell-free assays, bioactive agents, imaging probes, etc.).

Multidisciplinary Studies of HIV and Viral Hepatitis Co-Infection (R01)

The purpose of this Funding Opportunity Announcement (FOA) is to fill gaps in our understanding of a) the pathogenic interactions between HIV and hepatitis viruses, b) co-morbidities associated with HIV/hepatitis virus co-infection, and c) the effectiveness of interferon-free direct-acting antiviral drug regimens to treat HIV/HCV co-infection.

Exploratory Studies of Smoking Cessation Interventions for People with Schizophrenia (R21/R33)

The purpose of this Funding Opportunity Announcement (FOA) is to provide support for grant applications to generate and conduct preliminary tests of targeted smoking cessation treatments for individuals with schizophrenia. Smokers with schizophrenia who have co-occurring alcohol and/or substance abuse disorders are also a population of interest.

Exploratory Studies of Smoking Cessation Interventions for People with Schizophrenia (R33)

The purpose of this Funding Opportunity Announcement (FOA) is to provide support for grant applications of two major types. Type I will conduct exploratory testing of novel, targeted treatments for smoking cessation for individuals with schizophrenia. Type II will conduct exploratory testing of targeted implementation strategies of existing efficacious treatments at the service-delivery system level. Smokers with schizophrenia who have co-occurring alcohol and/or substance abuse disorders are also a population of interest.

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44)

The overarching goal of the SBIR program at the National Institute of Mental Health (NIMH) is to support small businesses to develop technologies that can advance the mission of the Institute, including in basic neuroscience research relevant to mental disorders, translational and clinical research of mental disorders, clinical diagnosis or treatment of mental disorders, and dissemination of evidence-based mental health care.

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)

The overarching goal of the Small Business Technology Transfer (STTR) program at the National Institute of Mental Health (NIMH) is to support small businesses to develop technologies that can advance the mission of the Institute, including basic neuroscience research relevant to mental disorders, translational and clinical research of mental disorders, clinical diagnosis or treatment of mental disorders, and dissemination of evidence-based mental health care.

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44)

This funding opportunity announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop technologies and approaches (i.e., novel ways to use new or existing technologies) that will enable researchers to study the structure and/or function of brain localized G-protein coupled receptor proteins (GPCRs) and/or potentially identify novel selective and specific agonists/antagonists to these receptor subtypes, with a focus on mental health function or dysfunction, including HIV-related neurocognitive disorders

Temporal Dynamics of Neurophysiological Patterns as Potential Targets for Treating Cognitive Deficits in Brain Disorders (R01)

A rich body of evidence suggests that cognitive processes are associated with particular patterns of neural activity. These data indicate that oscillatory rhythms, their co-modulation across frequency bands, spike-phase correlations, spike population dynamics, and other patterns might be useful drivers of therapeutic development for cognitive improvement in neuropsychiatric disorders. This initiative encourages applications to test whether modifying electrophysiological patterns during behavior can improve cognitive abilities.

Academic Research Enhancement Award (Parent R15)

The purpose of the Academic Research Enhancement Award (AREA) program is to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. AREA grants create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH research programs to contribute to the Nation's biomedical and behavioral research effort.

Extended Development, Hardening and Dissemination of Technologies in Biomedical Computing, Informatics and Big Data Science (R01)

The goal of this program announcement is to support the extended development, maintenance, testing, evaluation, hardening and dissemination of existing biomedical software. The NIH is interested in promoting a broad base of research and development of technologies in biomedical computing, informatics, and Big Data Science that will support rapid progress in areas of scientific opportunity in biomedical research.