Mental Health

Sustained Release of Antivirals for Treatment or Prevention of HIV (SRATP) (R01)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage grant applications that address the long term goal and objective of developing sustained release strategies for HIV treatment or prevention. Applications may propose treatment or prevention products delivered using sustained release platforms (oral, injection, implant or direct delivery to HIV target mucosa) that will provide a minimum of 1 week for oral (treatment) or a minimum of once a month for all other drug delivery systems for prevention and treatment protection/efficacy.

Systems Science and Health in the Behavioral and Social Sciences (R21)

This FOA is intended to increase the breadth and scope of topics that can be addressed with systems science methodologies. This FOA calls for research projects that are applied and/or basic in nature (including methodological and measurement development), have a human behavioral and/or social science focus, and employ methodologies suited to addressing the complexity inherent in behavioral and social phenomena, referred to as systems science methodologies.

Increased Knowledge and Innovative Strategies to Reduce HIV Incidence-iKnow Projects (R01)

The purpose of this Funding Opportunity Announcement (FOA) is to promote innovative research that addresses one or both of the following objectives: Devise optimal strategies to improve the identification of persons unaware of their HIV-1 infection and successfully link them to HIV testing, treatment, and prevention interventions. Develop and examine the feasibility and acceptability of novel integrated interventions of biomedical and behavioral strategies that substantially reduce the likelihood of onward HIV transmission in these populations.

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

The purpose of the Kirschstein-NRSA postdoctoral fellowship is to enhance the research training of promising postdoctoral candidates who have the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of the participating NIH Institutes and Centers.

Using the NIMH Research Domain Criteria (RDoC) Approach to Understand Psychosis (R21)

NIMH seeks applications which propose research studies that will use the NIMH's Research Domain Criteria (RDoC) framework to advance scientific understanding of neurobehavioral mechanisms related to psychotic symptoms (hallucinations, delusions, disorganized behavior, and thought disorder).

Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3)

The overall goal of this initiative is to identify neurophysiological measures as potential assays for treatment development research. The FOA will support efforts to optimize and evaluate measures of neurophysiological processes that are disrupted within or across mental disorders in both healthy humans and in another species relevant to the therapeutic development pipeline. The initiative will support initial proof of concept studies aimed at identifying measures for potential development as preclinical assays for evaluating potential new drug and device therapies and their targets.

Reducing the Duration of Untreated Psychosis in the United States (R34)

Approximately 100,000 adolescents and young adults in the United States experience a first episode of psychosis (FEP) every year. The early phase of psychotic illness is widely viewed as a critical opportunity for indicated prevention, and a chance to alter the downward trajectory and poor outcomes associated with schizophrenia and related psychotic disorders.

Revision Applications for Validation of Mobile/Wireless Health Tools for Measurement and Intervention (R01)

This Funding Opportunity Announcement (FOA) invites revision applications from investigators and institutions/organizations with active NIH-supported research project awards to support an expansion of the scope of approved and funded projects to incorporate recent advances in mobile/wireless tools to validate these tools for measurement and intervention delivery. Revision applications for projects that do not currently employ mobile/wireless tools are welcome provided that the applicant team has the requisite scientific and technical expertise to employ and validate these tools.

Clinical Studies of Mental Illness Not Involving Treatment Development, Efficacy, or Effectiveness Trials (Collaborative R01)

This Funding Opportunity Announcement (FOA) seeks to support collaborative clinical studies, not involving treatment development, efficacy, or effectiveness trials. Primary areas of focus include mental health genetics, biomarker studies, and studies of mental illnesses (e.g. psychopathology, neurodevelopmental trajectories of psychopathology). Applicants should respond to this FOA when two or more sites are needed to complete the study.

BD2K Open Educational Resources for Skills Development in Biomedical Big Data Science (R25)

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this Big Data to Knowledge (BD2K) R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs.