Mental Health

High Throughput Screening (HTS) to Discover Chemical Probes (R21)

This Funding Opportunity Announcement (FOA) encourages investigators to form collaborations with an established academic, nonprofit, or commercial high throughput screening (HTS) facility that has the requisite expertise and experience to implement HTS-ready assays for the discovery and development of small molecule chemical probes.

First in Human and Early Stage Clinical Trials of Novel Investigational Drugs for Psychiatric Disorders (U01)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage cooperative agreement applications to support early stage clinical trials of novel mechanism of action, investigational drugs or drug candidates for the treatment of psychiatric disorders in areas of unmet medical need. The FOA will support milestone-driven early stage trials in pediatric and adult populations.

NIH Pathway to Independence Award (Parent K99/R00)

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.

Innovative Basic Research on Adducts in Cancer Risk Identification and Prevention (R21)

This Funding Opportunity Announcement (FOA), encourages research projects focused on adducts to cellular macromolecules as indicators of exposures to cancer risk factors relevant to human populations. The priority is on projects that will focus on adductomic approaches, i.e., address some aspects of the totality of adducts. These projects should explore the basic aspects of adducts/adductomics that may have a potential utility in cancer detection, cancer prevention, and/or assessing cancer risks.

NIMH Administrative Supplement Program Providing Research Experiences for Physicians and Medical Students from Diverse Backgrounds

The purpose of the NIMH Administrative Supplement Providing Research Experiences for Physicians and Medical Students from Diverse Backgrounds is to support advanced research experiences for outstanding early career physicians and medical students from underrepresented backgrounds. This program aims to increase the opportunities available for individuals from underrepresented backgrounds working in the mental health research workforce by recruiting and supporting outstanding physician-scientists and medical students.

Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)

The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) to eligible, domestic institutions to enhance predoctoral and postdoctoral research training, including short-term research training, and help ensure that a diverse and highly trained workforce is available to meet the needs of the Nations biomedical, behavioral, and clinical research agenda.

Using the NIMH Research Domain Criteria (RDoC) Approach to Understand Psychosis (R01)

NIMH seeks applications which propose research studies that will use the NIMH's Research Domain Criteria (RDoC) framework to advance scientific understanding of neurobehavioral mechanisms related to psychotic symptoms (hallucinations, delusions, disorganized behavior, and thought disorder).

NIH Small Research Grant Program (Parent R03)

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.

NIH Research Project Grant (Parent R01)

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

Multidisciplinary Studies of HIV/AIDS and Aging (R21)

This FOA invites applications proposing to study HIV infection, HIV-associated conditions, HIV treatment, and/or biobehavioral or social factors associated with HIV/AIDS in the context of aging and/or in older adults. Research approaches of interest include clinical translational, observational, and intervention studies in domestic and international settings.