Study Details

Citation

Schnall, R., Kuhns, L. M., Pearson, C., Batey, D. S., Bruce, J., Hidalgo, M. A., Hirshfield, S., Janulis, P., Jia, H., Radix, A., Belkind, U., Rodriguez, R. G., & Garofalo, R. (2022). Efficacy of MyPEEPS Mobile, an HIV prevention intervention using mobile technology, on reducing sexual risk among same-sex attracted adolescent males: A randomized clinical trial. JAMA Netw Open, 5(9), e2231853. https://doi.org/10.1001/jamanetworkopen.2022.31853

Kuhns, L.M., Garofalo, R., Hidalgo, M. et al. A randomized controlled efficacy trial of an mHealth HIV prevention intervention for sexual minority young men: MyPEEPS mobile study protocol. BMC Public Health 20, 65 (2020). https://doi.org/10.1186/s12889-020-8180-4

Program or Component Study?
Program
Program or Component Name

MyPEEPS Mobile

Show Evidence of Effectiveness
Yes
Study Rating and Explanation
High

This study received a high study quality rating because it is a low-attrition randomized controlled trial with no known issues that would suggest the findings cannot be attributed to the program

Program Information

Program Type
Sexual health education

Evaluation Setting

Evaluation Setting
Community-based organization

Study Sample

Average Age Group
14 to 17
Majority Racial/Ethnic Group
Hispanic or Latino
Sex
Young male

Research Design

Assignment Method
Randomized controlled trial
Sample Size

763

Number of Follow-Ups

4

Length of Last Follow-Up

9 months after baseline

Year of Last Data Collection
2020

Study Findings

Result Number of Partners
Indeterminate evidence
Result Contraceptive Use
Potentially favorable evidence
Result STI or HIV
Indeterminate evidence
Reviewed Studies
High-Quality Randomized Trial
Protocol Version
Version 7.0
Details

MyPEEPS Mobile was evaluated using a randomized controlled trial involving same-sex attracted, male-identifying people ages 13 to 18 recruited through various social media sites and clinic-based recruitment events held in Birmingham, Alabama; New York, New York; Seattle, Washington; and Chicago, Illinois. Participants were randomly assigned to either an intervention group that immediately received access to the three-month, 21-module online program or a control group that received the same three-month program but administered on delay between months nine and 12 of the study period. Surveys were administered to both groups immediately at baseline and at three, six, and nine months (before the control group received the intervention). The delayed intervention group received an additional survey in month 12 following their completion of the program; the results of this survey were not included in this study.

The study found that at the three-month follow-up, young men participating in the intervention reported a statistically significant decrease in the number of condomless anal sex acts (insertive and receptive) with partners compared to the control group (effect size = -0.07). Differences in the number of condomless anal sex acts between the two groups were not significant at the six- and nine-month follow-ups.

The study also found that young men participating in the intervention and those in the control group were not significantly different in their number of sex partners and number of condomless anal sex partners at the three-, six-, and nine-month follow-ups, nor were they different in their HIV and STI testing.

The study also examined program impacts on pre-exposure prophylaxis (PrEP) uptake, post-exposure prophylaxis (PEP) use, and the number of sex acts under the influence of substances. Findings for these outcomes were not considered for the review because they fell outside the scope of the review.

Effect Sizes
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NA = Not available. This means the authors did not report the information in the manuscripts associated with the studies we reviewed.

a This information was not available whenever authors did not report information for the treatment and comparison groups separately on outcome means, standard deviations, and/or sample sizes.

b Authors reported that the program effect (impact) estimate is statistically significant with a p-value of less than 0.05 based on a two-tailed test.

c For some outcomes, having less of that outcome is favorable. In those cases, an effect with a negative sign is favorable to the treatment group (that is, the treatment group had a more favorable outcome than the comparison group, on average).

d An effect shows credibly estimated, statistically significant evidence whenever it has a p-value of less than 0.05 based on a two-tailed test, includes the appropriate adjustment for clustering (if applicable), and it is not based on an endogenous subgroup.

Language directly from the program model developer or authors.