Grants.gov

Description

This notice announces the opportunity to apply for funding under the Ryan White HIV/AIDS Program (RWHAP) Part D Women, Infants, Children, and Youth (Part D WICY or RWHAP Part D) Grants Supplemental Funding for fiscal year (FY) 2019. The purpose of this supplemental funding is to strengthen organizational capacity to respond to the changing health care landscape and increase access to high quality family-centered HIV primary health care services for low income, uninsured, and underserved WICY living with HIV. Funding under this program is intended to support one, short-term activity that can be completed by the end of the one-year funding opportunity period of performance. Applicants who were awarded supplemental funding for an HIV Care Innovation activity in FY 2018 through either the RWHAP Part D Supplemental (HRSA-18-044) or Part C Capacity Development (HRSA-18-051) may propose an expansion of these activities; however, HRSA will not fund the same activity in FY 2019 as HRSA funded in FY 2018 through HRSA-18-044 or HRSA-18-051. If the proposed project is an expansion of a previously funded activity, you will be required to provide a clear rationale for how the proposed activity builds upon and furthers the objectives of the previously funded HIV Care Innovation activity. HIV Care Innovation HIV Care Innovation activities support progress along the HIV care continuum to improve the health and life span of people living with HIV (PLWH) and prevent new infections. There are five (5) activities from which to choose. Patient-Based Treatment Adherence Motivational Interviewing Transitioning Youth into Adult HIV Care Intimate Partner Violence Screening and Counseling Youth Stable Housing Collaboration Collectively, activities will allow Part D programs to better align with priority areas for the Department of Health and Human Services (HHS) and the Health Resources and Services Administration (HRSA), including investing in addressing the opioid crisis, mental health, and promoting collaboration. The selected activity should target populations that are disproportionately affected by the HIV epidemic and have poor health outcomes. Furthermore, you must demonstrate that the proposed activity will strengthen organizational capacity to respond to the changing health care landscape and increase access to high quality HIV primary health care services for low income, uninsured, and underserved PLWH.

Description

The purpose of this Funding Opportunity Announcement (FOA) is to provide opportunities for eligible small business concerns (SBCs) to submit STTR grant applications to develop interactive digital media science, technology, engineering and mathematics (STEM) resources that address student career choice and health and medicine topics for: (1) pre-kindergarten to grade 12 (P-12) students and pre- and in-service teachers ("Teachers") or (2) Informal science education (ISE), i.e., outside the classroom, audiences. Interactive digital media (IDM) are defined as products and services on digital computer-based systems which respond to the user's actions by presenting content such as text, moving image, animation, video, audio, and video games. There is a large body of evidence that IDM technology has the potential to support learning in a variety of contexts from primary and secondary schools, to universities, adult education and workplace training. IDM is widely used to train, educate, and encourage behavioral changes in a virtual world format where progressive learning, feedback on success and user control are combined into an interactive and engaging experience. It is anticipated that this STTR FOA will facilitate the translation of new or existing health and medicine-based, P-12 STEM curricula and museum exhibits into educational Interactive Digital Media STEM (IDM STEM) resources that will provide a hands-on, inquiry-based and learning-by-doing experience for students, teachers and the community.

Description

The purpose of this funding opportunity announcement (FOA) is to foster research on the unique perspectives, needs, wishes, and decision-making processes of adolescents and young adults (AYA; defined by the World Health Organization and the Centers for Disease Control and Prevention as youth between 12 24 years of age) with serious, advanced illnesses; and research focused on specific end-of-life/palliative care (EOLPC) models that support the physical, psychological, spiritual, and social needs of AYA with serious illness, their families and caregivers.

Description

The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory/developmental research to improve self-management and quality of life in children and adolescents with chronic conditions. Managing a chronic condition is an unremitting responsibility for children and their families. Children with a chronic condition and their families have a long-term responsibility for self-management. This FOA encourages research that takes into consideration various factors that influence self-management such as individual differences, biological and psychological factors, family/caregivers and sociocultural context, family-community dynamics, healthcare system factors, technological advances, and the role of the environment.

Description

This Funding Opportunity Announcement (FOA), issued by the National Institute of Nursing Research (NINR), is to encourage Exploratory/Developmental Research Grant (R21) applications that employ innovative research to identify mechanisms of influence and/or promote positive sustainable health behavior(s) in children and youth (birth to age 18). Positive health behaviors may include: developing healthy sleep patterns, developing effective self-regulation strategies, adaptive decision-making in risk situations, practicing proper dental hygiene, eating a balanced and nutritious diet, engaging in age-appropriate physical activity and/or participating in healthy relationships. Applications to promote positive health behavior(s) should target social and cultural contexts, including, but not limited to: schools, families, communities, population, food industry, age-appropriate learning tools and games, social media, social networking, technology and mass media. Topics to be addressed in this announcement include: effective, sustainable processes for influencing young people to make healthy behavior choices; identification of the appropriate stage of influence for learning sustainable lifelong health behaviors; the role of technology and new media in promoting healthy behavior; identification of factors that support healthy behavior development in vulnerable populations; and, identification of mechanisms and mediators that are common to the development of a range of habitual health behaviors. Given the many factors involved in developing sustainable health behaviors, applications from multidisciplinary team that include nurse scientists are strongly encouraged. The goal of this FOA is to promote research that identifies and enhances processes that promote sustainable positive behavior or changes social and cultural norms that influence health and future health behaviors.

Description

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Curriculum or Methods Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients, in accordance with the overall mission of the NCI.

Description

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research applications to develop and test the effectiveness and implementation of family navigator models designed to promote early access, engagement and coordination of mental health treatment and services for children and adolescents who are experiencing early symptoms of mental health problems. For the purposes of this FOA, NIMH defines a family navigator model as a health care professional or paraprofessional whose role is to deploy a set of strategies designed to rapidly engage youth and families in needed treatment and services, work closely with the family and other involved treatment and service providers to optimize care and monitor the trajectory of mental health symptoms and outcomes over time. Applicants are encouraged to develop and test the navigator models ability to promote early access, engagement and coordination of mental health treatment and services for children and adolescents as soon as symptoms are detected. Of interest are navigator models that coordinate needed care strategies, determine the personalized match to the level of needed service amount, frequency and intensity, and harness novel technologies to track and monitor the trajectory of clinical, functional and behavioral progress toward achieving intended services outcomes. This FOA is published in parallel to a companion R34 FOA PAR-18-429 supporting pilot studies in preparation for the larger-scale studies described here.

Description

This initiative supports research to test the effectiveness of combined strategies to both detect and intervene to reduce the risk of suicide behavior, suicide ideation, and non-suicidal self-harm (NSSI) by youth in contact with the juvenile justice system. Opportunities for detection and prevention start at early points of contact (e.g., police interaction, the intake interview) and continue through many juvenile justice settings (e.g., pre-trial detention, juvenile or family court activities, court disposition, placement and on-going care in either residential or multiple community settings.) This FOA invites intervention strategies that are designed to be delivered in typical service settings using typically available personnel and resources, to enhance the implementation of interventions that prove effective, enhance their future uptake in diverse settings, and thereby reduce risk of suicide and self-harm in this population. This FOA is published in parallel to a companion R34 FOA (PAR-xx-xxx) supporting pilot studies in preparation for the larger-scale studies described here.

Description

This Funding Opportunity Announcement encourages developmentally tailored research focused on adolescents and emerging adults as it relates to HIV prevention and treatment. Research is encouraged to incorporate recent advances in adolescent and young adult developmental research to optimize outcomes in HIV prevention and care research for this heterogeneous population. PA-FY-NNN uses the R01 grant mechanism, PA-FY-NNN uses the R21 mechanism, while PA-FY-NNN uses the R34 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism. Applicants with preliminary data and/or planning to include longitudinal analysis may wish to apply using the R01 mechanism. Applicants wanting to develop and pilot test an intervention may wish to apply using the R34 mechanism.

Description

This Funding Opportunity Announcement encourages developmentally tailored research focused on adolescents and emerging adults as it relates to HIV prevention and treatment. Research is encouraged to incorporate recent advances in adolescent and young adult developmental research to optimize outcomes in HIV prevention and care research for this heterogeneous population. PA-FY-NNN uses the R01 grant mechanism, PA-FY-NNN uses the R21 mechanism, while PA-FY-NNN uses the R34 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism. Applicants with preliminary data and/or planning to include longitudinal analysis may wish to apply using the R01 mechanism. Applicants wanting to develop and pilot test an intervention may wish to apply using the R34 mechanism.

Description

Note: Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. For the addresses for obtaining and submitting an application, please refer to our Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on February 12, 2018 (83 FR 6003) and available atwww.gpo.gov/fdsys/pkg/FR-2018-02-12/pdf/2018-02558.pdf. The dates when applications are available and the deadlines for transmittal of applications invited under this notice are indicated in the chart at the end of this notice and in the Requests for Applications (RFAs) that are posted at the following websites: https://ies.ed.gov/funding,https://www.ed.gov/programs/edresearch/index.... https://www.ed.gov/programs/specialedresearch/index.html. FOR FURTHER INFORMATION CONTACT: The contact person associated with a particular research competition is listed in the chart at the end of this notice, as well as in the relevant RFA and application package. Purpose of Program: In awarding these grants, the Institute of Education Sciences (Institute) intends to provide national leadership in expanding fundamental knowledge and understanding of (1) developmental and school readiness outcomes for infants and toddlers with or at risk for a disability, (2) education outcomes for all students from early childhood education through postsecondary and adult education, and (3) employment and wage outcomes when relevant (such as for students who engaged in career and technical, postsecondary, or adult education). The Institute's research grant programs are designed to provide interested individuals and the general public with reliable and valid information about education practices that support learning and improve academic achievement and access to education opportunities for all students. These interested individuals include parents, educators, students, researchers, and policymakers. In carrying out its grant programs, the Institute provides support for programs of research in areas of demonstrated national need. Competitions in This Notice: The Institute will conduct nine research competitions in FY 2019 through two of its centers: The Institute's National Center for Education Research (NCER) will hold a total of five competitions--one competition in each of the following areas: Education research; education research and development centers; statistical and research methodology in education; partnerships and collaborations focused on problems of practice or policy; and low-cost, short-duration evaluation of education interventions. Catalog of Federal Domestic Assistance (CFDA) numbers 84.305A, 84.305C, 84.305D, 84.305H, 84.305L, 84.324A, 84.324B, 84.324L, and 84.324N.

Description

This Funding Opportunity Announcement (FOA), issued by the National Institute of Nursing Research (NINR), is intended to encourage Research Project Grant (R01) applications that employ innovative research to identify mechanisms of influence and/or promote positive sustainable health behavior(s) in children and youth (birth to age 18). Positive health behaviors may include: developing healthy sleep patterns, developing effective self-regulation strategies, adaptive decision-making in risk situations, practicing proper dental hygiene, eating a balanced and nutritious diet, engaging in age-appropriate physical activity and/or participating in healthy relationships. Applications to promote positive health behavior(s) should target social and cultural contexts, including, but not limited to: schools, families, communities, population, food industry, age-appropriate learning tools and games, social media, social networking, technology and mass media. Topics to be addressed in this announcement include: effective, sustainable processes for influencing young people to make healthy behavior choices; identification of the appropriate stage of influence for learning sustainable lifelong health behaviors; the role of technology and new media in promoting healthy behavior; identification of factors that support healthy behavior development in vulnerable populations; and, identification of mechanisms and mediators that are common to the development of a range of habitual health behaviors. Given the many factors involved in developing sustainable health behaviors, applications from multidisciplinary team that include nurse scientists are strongly encouraged. The goal of this FOA is to promote research that identifies and enhances processes that promote sustainable positive behavior or changes social and cultural norms that influence health and future health behaviors.

Description

An innovative science, technology, engineering, mathematics and computing (STEM+C) workforce and well-educated citizenry are crucial to the Nation's prosperity, security and competitiveness. Preparation for the future workforce must begin in the earliest grades from preK-12, where students need to learn not only the science and mathematics central to these areas, but also how computational thinking is integral to STEM disciplines. Because of the powerful innovation and application of computing in STEM disciplines there is an urgent need for real-world, interdisciplinary, and computational preparation of students from the early grades through high school (preK-12) that will provide a strong foundation for mid-level technical careers and for continuing education in higher education. This is particularly important in the key science areas described in the National Science Foundation’s Big Ideas for Future NSF Investment. The STEM+C program supports research and development proposals related to new approaches to pre-K-12 STEM teaching and learning related to Harnessing the Data Revolution, Convergence Research and the Future of Work at the Human-Technology Frontier. The STEM+C Program focuses on research and development of interdisciplinary and transdisciplinary approaches to the integration of computing within STEM teaching and learning for preK-12 students in both formal and informal settings. The STEM+C program supports research on how students learn to think computationally to solve interdisciplinary problems in science and mathematics. The program supports research and development that builds on evidence-based teacher preparation or professional development activities that enable teachers to provide excellent instruction on the integration of computation and STEM disciplines. Proposals should describe projects that are grounded in prior evidence and theory, are innovative or potentially transformative, and that will generate and build knowledge about the integration of computing and one or more STEM disciplines at the preK-12 level. A proposal submitted to this program description should describe the integration of computing with one or more STEM disciplines. A proposal may focus on studies on the effects of integrating computational thinking with STEM disciplines or the challenges of implementing these potentially disruptive educational interventions. Proposed projects may develop models, assessments, and technological tools to support teaching and learning in this area as well as conduct research on these models, assessments, and tools. Outcomes of projects should enable the Nation to have a future workforce with knowledge of computational thinking integrated with STEM disciplines, and students prepared and interested in careers in the skilled technical work force or further education and science careers.

Description

This notice announces the opportunity to apply for funding under the Family-to-Family Health Information Centers (F2F HICs) Program. The purpose of this program is to provide information, education, technical assistance, and peer support to families of children and youth with special health care needs (CYSHCN) and the professionals who serve them.

Description

The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2019 Project AWARE (Advancing Wellness and Resilience in Education) - State Education Agency (SEA) grants (Short Title: AWARE-SEA). The purpose of this program is to build or expand the capacity of State Educational Agencies, in partnership with State Mental Health Agencies (SMHAs) overseeing school-aged youth and local education agencies (LEAS), to: (1) increase awareness of mental health issues among school-aged youth; (2) provide training for school personnel and other adults who interact with school-aged youth to detect and respond to mental health issues; and (3) connect school-aged youth, who may have behavioral health issues (including serious emotional disturbance [SED] or serious mental illness [SMI]), and their families to needed services. SAMHSA expects that this program will focus on partnerships and collaboration between state and local systems to promote the healthy development of school-aged youth and prevent youth violence. The AWARE-SEA program supports the development and implementation of a comprehensive plan of activities, services, and strategies to decrease youth violence and support the healthy development of school-aged youth. This program builds upon the successful strategies of the Safe Schools/Healthy Students (SS/HS) Initiative that have been effective in creating safe and secure schools and promoting the mental health of students in communities across the country. These strategies include facilitating a closer relationship between state and local implementation of policies and programs, and supporting the development of integrated systems that create safe and respectful environments for learning and promote the mental health of school-aged youth.

Description

The Department of Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program aims to increase the quantity and quality of minority professionals in science, technology, engineering, and mathematics (STEM) in the defense community. Research conducted at Minority-Serving Institutions (MSIs) for the DoN HBCU/MI Program: • Enhances the research and educational capabilities of HBCU/MIs in scientific and engineering disciplines critical to the defense mission of the DoN, • Encourages cross-institutional, collaborative participation of HBCU/MIs in naval-relevant research, development, testing, and evaluation (RDT&E), and • Increases the engagement of students, including underrepresented minorities, in STEM fields important to the defense mission. This FOA is executed under policy and guidance of the DoN HBCU/MI Program and is administered by the Office of Naval Research (ONR). This FOA seeks to support research efforts that will contribute to the science and technology (S&T) mission and vision of the U.S. Navy and the U.S. Marine Corps while simultaneously expanding the research capacity of participant institutions and engaging students in STEM. In that regard, this FOA is intended for white papers and invited proposals from HBCU/MIs exploring basic, naval-relevant research. The technical content of any idea must align with the following research areas of interest as outlined by the Naval Research Development Framework. Information, Cyber, and Spectrum Superiority An increasingly interconnected force with more rapid and effective decision-making is enabled by persistent sensing, advanced data analytics, digital integration, and assured spectrum access. In that regard, this research area spans three strategic areas: • Assured Command and Control (C2) • Electromagnetic Maneuver Warfare (EMW) • Full Spectrum Cyber technologies Assured Command and Control (C2): Assured C2 is enabled by persistent sensing, timely intelligence, and decision support tools that will accelerate “data to decisions” timelines. Leveraging machine reasoning and data analytics, an end-to-end approach achieves protected data transport, resilient networking, and assured apps and services that result in trusted information and actions. The need for increased spectral efficiency and diversity, coupled with the information domain, is critical to our naval freedom of maneuver on a global scale. Electromagnetic Maneuver Warfare (EMW): EMW efforts include electromagnetic spectrum management technologies and techniques that fluidly combine communications, surveillance electronic warfare (EW), and electronics to understand and shape the battlespace. Ultra-wide bank systems, which continuously monitor the spectrum, are needed to facilitate optimized use. Intrinsically secure and resilient computing systems with robust computational and communications architectures will provide the capability to manipulate and interpret rapidly growing amounts of data support of C2, Combat Systems (CS), and Intelligence Surveillance, and Reconnaissance (ISR) effects. Assuring secure access to the full spectrum is essential to operate at will or deny adversary access in more complex and dynamic future EMW environments. Full Spectrum Cyber technologies: Full-spectrum Cyber approaches must be developed to protect our networks, data, information systems, and real-time control systems. Total platform cyber protection is becoming an essential element of Information Warfare. Cyber technologies provide the ability to assess and counter potential threats. Future information systems must provide agile capabilities for achieving and maintaining communications and data integrity in rapidly evolving, dispersed, and disadvantaged environments. Computational architectures need more resilient information infrastructure through assured system design, automated defensive tools for advanced persistent threats, hardening of the hosts, and data assurance. Applicable Research Interests: • Advanced RF electronics and materials • Communications and networking • Computational methods for decision making • Data science and analytics • Electronic warfare • Sensors and sensor processing • Machine learning, reasoning, and intelligence • Resource optimization • Precision navigation and timekeeping Mission Capable, Persistent, and Survivable Sea Platforms Concepts, systems, and component technologies that improve the performance and survivability of naval ships/submarines in an increasingly distributed yet interconnected force are critical. New platforms will need to deliver advanced weapons, as well as increased mobility and survivability. Power and energy for surface ships is a key, enduring investment for the efficiency of legacy platforms, while enabling the power requirements of future electric weapons. High-power electric weapons and sensors have advanced significantly, creating technical requirements for dramatic increases in energy management and pulsed power. Computational tools that model the platform’s interaction with the anticipated operational environment are essential to the development of integrated designs and protections such as stealth, counter-directed energy weapons, tactical decision aids, electronic warfare, and hard-kill systems. Undersea dominance remains a priority as the Navy designs and builds the next generation of strategic and tactical submarines. Resurgence by peer adversaries in ultra-quiet submarine technology is closing the gap in undersea warfare. Platform mobility and survivability is critical to successful operational strategies calling for more distributed forces. Advancements in materials, acoustics, and intelligent control are required in addition to hydro-, electro-, and computational mechanics. Advancements in countermeasures for ships and submarines are also critical. Platforms will become more self-sustaining to extend endurance and forward presence while reducing the logistics tail for fuel. Future platforms must have reduced sustainment requirements and be easier to maintain. Efforts are focused on platform interfaces as well as platform efficiency to reduce sustainment needs. Enhanced interface standards and modularity provide flexibility, ease of maintenance, and upgrades. Finally, affordability permeates all modernization concepts. The development of validated design tools capable of rapidly and accurately analyzing and evaluating novel platforms with advanced system performance characteristics is a high priority. Applicable Research Interests: • Naval engineering • Advanced naval power systems • Advanced survivable sea platforms • Unmanned sea platforms, autonomy, and power • Advanced naval materials • Undersea weapons, counter-weapons, and energetics • Sea platform environmental quality • Corrosion control Aviation, Force Projection, and Integrated Defense Sea-based aviation, including platform and weapons research, is focused on new or enhanced capabilities to defined against, and/or deter, disable, damage, defeat, or destroy adversaries at extended ranges and speeds. Offsetting technologies must continue to provide naval forces with an edge in any future battle. In the future battlespace, electric weapons with deep magazines and low cost-per-kill will be required to engage large numbers of threats simultaneously. Directed-energy systems will be used in layered defense to counter ISR capabilities, defeat or destroy threats, both before and during combat. Networked weapons will improve the probability to kill and reduce the need for multiple weapons targeting the same platform. Advanced warhead materials will decrease the size of rounds. Electromagnetic realigns will allow more, smaller, and longer-range rounds. Future naval fires efforts include targeting, decision support and precision strike by air, surface, undersea, and expeditionary forces. Improved aerodynamic control will allow unprecedented maneuverability for unconventional aircraft designs. Advanced aircraft power and propulsion technologies, such as variable-cycle advanced technology, will provide more efficient operation over a wider range of flight conditions. They will also enable technologies for providing the power and thermal management of electric weapons for next-generation aircraft. Advances in structures and materials will allow for reduced life-cycle costs as well as stronger and lighter airframes. Autonomous systems will reduce operational risk and improve mission performance. For today’s missions, autonomy can improve manning effectiveness and provide options for mission tasks. For future missions, autonomy can provide new persistent, pervasive, and rapid response capabilities to do tasks that would be unaffordable or impractical today.

Description

The Office of Global Educational Programs of the Bureau of Educational and Cultural Affairs (ECA) of the U.S. Department of State announces an open competition for the Community College Initiative (CCI) Program. ECA is seeking proposal submissions for one cooperative agreement to design, implement, and oversee the CCI Program. The CCI Program provides international participants from underserved and underrepresented communities with an intensive academic-year long program at accredited U.S. community colleges, focused on building technical and professional skills while deepening participants' understanding of the United States, its people and values.

Description

NIST invites applications from eligible applicants for the development, production and distribution of science and/or mathematics curricula resources for high school classrooms that reflect the redefinition of units within the international system of measurement (also called the metric system).

Description

This FOA is intended to solicit two-phase research applications to develop, adapt and test interventions and strategies to prevent initiation of opioid misuse and development of OUD in at-risk older adolescents and young adults (ages 16-30). The goal is to stimulate research studies conducted in populations and geographic areas most affected by the opioid crisis or with indicators of an emerging crisis. Of priority are studies that target older adolescents and young adults in health care settings (including primary care, surgical, orthopedic and other specialty care, dental care, emergency departments, urgent care, HIV/STI and reproductive health clinics, prenatal clinics, school-based health centers, federally qualified health centers, military medicine settings, occupational health settings), justice settings (including criminal justice, juvenile justice, as well as child welfare and other systems that cross with the justice system) and other systems and settings. Studies that include understudied at-risk older adolescent and young adult populations are strongly encouraged. Examples include, but are not limited to individuals in rural or reservation settings, women, veterans, and individuals with a history of polysubstance use or mental disorders.

Description

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer cohorts to elucidate the genetic contribution to childhood cancers, or to expand the range of disorders included within the Kids First Data Resource to investigate the genetic etiology of structural birth defects. Whole genome, exome, and transcriptome sequencing may be available for tumor or affected tissue when justified. These data will become part of the Gabriella Miller Kids First Pediatric Data Resource (Kids First Data Resource) for the pediatric research community.