Study Details

Citation

Bryan , A. D., Magnan, R. E., Gillman, A. S., Yeater, E. A., Feldstein Ewing, S. W., Kong, A. S., & Schmiege, S. J. (2018). Effect of including alcohol and cannabis content in a sexual risk-reduction intervention on the incidence of sexually transmitted infections in adolescents: A cluster randomized clinical trial. JAMA Pediatrics, 172(4), e175621.

Schmiege , S. J., Magnan, R. E., Yeater, E. A., Ewing, S. W. F., & Bryan, A. D. (2021). Randomized trial to reduce risky sexual behavior among justice-involved adolescents. American Journal of Preventive Medicine, 60(1), 47–56.

Program or Component Study?
Program component
Program or Component Name

Cannabis program content implemented as a supplement to a sexual risk reduction intervention that also included alcohol program content

Show Evidence of Effectiveness
No
Study Rating and Explanation
High

This study received a high study quality rating because it is a low-attrition randomized controlled trial with no known issues that would suggest the findings cannot be attributed to the program

Program Information

Program Type
Programs for special populations
Sexual health education
Program Length
Fewer than 10 sessions

Evaluation Setting

Evaluation Setting
Correctional facility

Study Sample

Average Age Group
14 to 17
Majority Racial/Ethnic Group
Hispanic or Latino
Sex
Male and female youth

Research Design

Assignment Method
Cluster randomized controlled trial
Sample Size

317

Number of Follow-Ups

4

Length of Last Follow-Up

12 months after end of intervention

Year of Last Data Collection
2014

Study Findings

Result STI or HIV
Indeterminate evidence
Reviewed Studies
High-Quality Randomized Trial
Protocol Version
Version 7.0
Details

Cannabis program content implemented as a supplement to a sexual risk reduction intervention that also included alcohol program content, was evaluated using a cluster randomized control trial involving young men and women living at a detention facility in the Southwest United States at the time of study recruitment. Participants were randomly assigned in same-sex groups to one of three interventions: (1) a sexual risk reduction intervention (SRRI); (2) a sexual risk reduction intervention supplemented with an alcohol content component (SRRI + ETOH); or (3) a sexual risk reduction intervention supplemented with an alcohol and cannabis content component (SRRI + ETOH + THC). Surveys were administered immediately before the intervention (baseline) and three, six, nine, and 12 months after the end of the intervention. Urine tests were administered at baseline and 12 months after the end of the intervention to diagnose Chlamydia trachomatis and Neisseria gonorrhoeae.

At the 12-month follow-up, the authors found that youth who received the cannabis content component (THC), in addition to the SRRI and ETOH components, did not significantly differ in terms of testing positive for STIs from the group that only received the SRRI and ETOH components. The authors reported an odds ratio of 0.36, with a 95 percent confidence interval ranging from .12-1.05; however, because this confidence interval crossed 1, the impact was deemed to be non-significant.

The study also examined the cannabis component impacts on frequency of unprotected sex at the three-, six-, nine-, and 12-month follow-ups. Findings for this outcome were not considered for the review because they did not meet the review evidence standards. Specifically, the findings for the frequency of unprotected sex outcome received a low rating.

Language directly from the program model developer or authors.